Many application support automation through the Open Sound Control (OSC) protocol. This is a network protocol that uses UDP and usually requires the client/server applications to be on the same network sub-net (IP address range).
An example of such and application is Resolume.
There is a great .Net library that can be used with PowerShell to send OSC messages to applications which support OSC. Download it from GitHub
Example PowerShell script to play a clip in Resolume
add-type -path 'C:\Users\imorrish\OneDrive\PowerShell\OSC\SharpOSC.dll' #Connection for Resolume $sender = new-object SharpOSC.UDPSender "192.168.1.67", 7000 #start a layer clip $message = new-object SharpOSC.OscMessage "/layer3/clip1/connect", 1; $sender.Send($message); #Enable or dissable a video effect on a clip. 1 = disable, 0 = enabled $message = new-object SharpOSC.OscMessage "/activeclip/video/effect1/bypassed", 1; $sender.Send($message);